Charles River are dedicated to helping you accelerate research and drug development. Their essential products and services empower pharmaceutical, biotech, government, and academic teams to turn possibilities into breakthroughs. From discovery to early development and safe manufacturing, they provide the solutions you need to bring new therapies to patients faster.
Endosafe® Endotoxin Testing Systems
A suite of scalable Endosafe® platforms support a variety of testing techniques, regardless of sample type, volume, or industry, from traditional kinetic methods, real-time single samples, to high-throughput fully automated instruments. All systems support both Endosafe LAL and Trillium™ rCR to provide testing flexibility and efficiencies.
Endosafe® Nexus 200™
Endosafe® nexgen-MCS™
Multi-Cartridge Endotoxin
Testing System
The Endosafe® nexgen-MCS™ supports the ability to test multiple endotoxin samples at once, via both Endosafe® LAL and Trillium™ recombinant cascade reagent (rCR) cartridges. The benchtop system houses five individual spectrophotometers in a single unit and is capable of testing 5 samples in approximately 15 minutes, reducing downtime by allowing random access of samples by not having to wait for a full batch before testing. Linked through a single Ethernet connector, the system is powered through an external PC with our 21 CFR Part 11 compliant-ready endotoxin measuring and analysis software, Endosafe® EndoScan-V™.
To learn more contact us today:
phone: +852 2856 0606 or email: admin@guyline-asia.com
Endosafe® nexgen-PTS™
Portable Endotoxin Testing System
The Endosafe® nexgen-PTS is a rapid, point-of-use handheld spectrophotometer. Supporting both Endosafe® LAL and Trillium™ recombinant cascade reagent (rCR) cartridges, it provides accurate and effortless endotoxin detection and glucan concentration determination. Its compact and lightweight footprint makes it optimal for small to mid-size pharmaceutical companies and compounding pharmacies requiring fast and simple testing right on the manufacturing floor.
To learn more contact us today:
phone: +852 2856 0606 or email: admin@guyline-asia.com
Celsis Adapt™ Sample Concentrator System
A One-Stop Solution for All Your Cell Culture Samples
The Celsis Adapt™ Sample Concentrator is the latest addition to the Celsis® rapid microbiological detection platform, designed specifically to remove non-microbial sample components, such as cellular debris found in cell and gene therapies, as well as preservatives and antimicrobial agents in cosmetics and personal care samples. Compatible with both the Celsis Accel® and Celsis Advance II™ instruments, the Celsis Adapt is the perfect accessory system to further unlock the potential of Celsis ® ATP-bioluminescence for cell-based therapies and faster results.
To learn more contact us today:
phone: +852 2856 0606 or email: admin@guyline-asia.com
Celsis Accel® System
Rapid Microbial Limit and Sterility Test Results for Microbiology Quality Control
Easy to use and easy to learn, the Celsis Accel® system delivers results in just 24-36 hours for microbial limits (USP <61>) quality control testing and 6 days for sterility testing (USP <71>), allowing you to rapidly confirm product quality and expedite release to market.
-
Shorten production cycle times
-
Decrease working capital requirements as well as safety stock
-
Reduce inventory requirements and warehouse space costs
-
Receive earlier notification in the event of a contamination
-
Respond to contamination and conduct investigations faster
To learn more contact us today:
phone: +852 2856 0606 or email: admin@guyline-asia.com
Celsis Advance II™ ATP Luminometer Platform
Easy and Secure Rapid Microbial Detection
The Celsis Advance II™ ATP Luminometer Platform delivers results in just 24-36 hours for microbial limits (USP <61>) quality control testing and 6 days for sterility testing (USP <71>), allowing you to rapidly confirm the quality of your products and quickly release them to market.
-
Shorten production cycle times
-
Decrease working capital requirements as well as safety stock
-
Reduce inventory requirements and warehouse space costs
-
Receive earlier notification in the event of a contamination
-
Respond to contamination and conduct investigations faster
To learn more contact us today:
phone: +852 2856 0606 or email: admin@guyline-asia.com
Endosafe® Endotoxin Testing Cartridges
This technology was designed to streamline and optimize testing by consolidating all the essential components into a single disposable cartridge, to provide real-time, quantitative endotoxin analysis. Available in Endosafe LAL and in 2024 Trillium rCR, with further commitment to the 3Rs by reducing and or replacing the usage of horseshoe crabs.
Endosafe® Endotoxin
Testing Cartridges
The Endosafe® cartridge technology is innovative offering higher sensitivity and faster quantitative LAL testing results. Designed to optimize and refine use of LAL, the cartridge technology eliminates a significant amount of the raw material and accessories required for traditional endotoxin testing methods while reducing time-consuming preparation and technician variability.
Endosafe® Trillium™
rCR Cartridges
The animal-free Endosafe® Trillium™ rCR cartridges are fueled by optimized kinetic chromogenic reagents curated to simulate the natural LAL reaction, fully embracing the significance of sustainability, while accelerating testing times through our scalable suite of rapid, automated testing platforms.
Endosafe® Beta-Glucan Cartridges
The (1,3)-b-D glucan molecules can be found in the cell walls of most yeasts and molds. These glucans contaminate cell culture fluid, yeast protein production, air quality samples, and cellulose filter preparations. Allow us to help you ensure that your product is free of glucans and isn’t triggering false-positive results in the LAL test leading to potential investigations.
To learn more contact us today:
phone: +852 2856 0606 or email: admin@guyline-asia.com
Endosafe® Endotoxin Testing Reagents
A complete and optimized portfolio of extremely precise and reliable LAL and rCR formulations provide increased sensitivity, greater linearity, and superior interference resistance. From raw materials, in-process, through final product release, explore an extensive offering of Endosafe® reagents and accessories to support your testing program.
Traditional LAL Kinetic Chromogenic Assay
Endochrome-K™ traditional LAL kinetic chromogenic assay reagent is a fully quantitative and uniquely stable reagent. The stability of the reconstituted LAL allows for extended bench time and reuse making it a highly cost-effective and rapid solution for endotoxin testing. How could the rapid results of Endochrome-K, advance your laboratory?
LAL Kinetic Turbidimetric Assay
The kinetic turbidimetric endotoxin test is designed to provide accurate and reliable results on even your most difficult products. The kinetic turbidimetric endotoxin test reagents (KTA and KTA2) allow optimized testing with a single FDA-licensed product that performs both kinetic and gel-clot analysis.
Gel-Clot Endotoxin Test
An inaccurate endotoxin test result can not only halt your production, it can also put patients at risk. Accurate gel-clot assay results ensure the safety of your pharmaceuticals. The gel-clot endotoxin test is a simple qualitative method best used for low-volume laboratories or for products such as those that are highly viscous or extremely colorful.
Endosafe® Trillium™ Recombinant Cascade Reagent (rCR)
A robust, animal-free recombinant cascade reagent (rCR), Endosafe® Trillium™ is the latest addition to Charles River's trusted and industry-leading Endosafe portfolio, and was developed with superior science, and designed for sustainable progress in the lab.
To learn more contact us today:
phone: +852 2856 0606 or email: admin@guyline-asia.com
Microbial Identification and Strain Typing
You can’t ensure product quality without control over your manufacturing environment. Accugenix® microbial identification and strain typing services provide accurate, reliable environmental monitoring (EM) data, so you can remain confident that your products are free of contamination.
Accugenix® Microbial Identification Services
Accurate and timely microbial identification is crucial for tracking and trending environmental monitoring data that guide critical decisions and protect you from releasing contaminated products. With more than 620,000 environmental isolates processed every year through Accugenix microbial identification service labs, they continuously expand their organism libraries based on real samples frequently recovered from QC labs and manufacturing sites around the world.
Accugenix® Sample Submission
Sample submission of your bacterial or fungal isolates for analysis via our Customer Web Portal is simple and fast. Sample submission and sample shipping can be completed in three easy steps.
Follow the three simple steps for sample submission and sample shipping to Charles River's Accugenix® laboratories for accurate, rapid microbial identification and strain typing results.
Mastering Microbial Identification with Accugenix® Brochure
From in-house testing to outsourced services, this Accugenix® brochure provides critical insights to help you choose the best microbial identification approach. Backed by 35+ years of experience in the field, serving organizations of all sizes in sterile and non-sterile pharmaceuticals, home and personal care, and beyond, to help you maintain the highest standards in microbial identification.
Download the Accugenix® brochure.
Axcess® MALDI-TOF for Microbiology Testing
The Axcess® Microbial Identification System features the precision of the Bruker MALDI Biotyper instrument with the industry-leading Accugenix® proprietary microbial libraries through a secure online network. The MALDI-TOF identification system instrument combined with validated microbial databases provides all of the tools needed for accurate and fast organism identifications.
To learn more contact us today:
phone: +852 2856 0606 or email: admin@guyline-asia.com
Contact Us
To learn more about Charles River's extensive portfolio of products which support a variety of testing techniques, regardless of sample type, volume or industry, contact us today:
phone: +852 2856 0606 or email: admin@guyline-asia.com
Let our experience be your success